A validated lineage-derived somatic truth data set enables benchmarking in cancer genome analysis
نویسندگان
چکیده
منابع مشابه
FaSD-somatic: a fast and accurate somatic SNV detection algorithm for cancer genome sequencing data
UNLABELLED Recent advances in high-throughput sequencing technologies have enabled us to sequence large number of cancer samples to reveal novel insights into oncogenetic mechanisms. However, the presence of intratumoral heterogeneity, normal cell contamination and insufficient sequencing depth, together pose a challenge for detecting somatic mutations. Here we propose a fast and an accurate so...
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ژورنال
عنوان ژورنال: Communications Biology
سال: 2020
ISSN: 2399-3642
DOI: 10.1038/s42003-020-01460-9